Everything You Need to Know About Citalopram (Celexa)
Citalopram, commonly known by its brand name Celexa, is a widely prescribed antidepressant that can help improve mood, reduce anxiety, and manage obsessive thoughts. If you’re considering citalopram or just want to learn more about it, this guide breaks it down in simple, easy-to-understand terms.
What is Citalopram?
Citalopram is a selective serotonin reuptake inhibitor (SSRI). It works by increasing the levels of serotonin—a key brain chemical that regulates mood, sleep, and emotions. By blocking serotonin from being reabsorbed too quickly, citalopram helps keep more serotonin available in your brain, which can improve symptoms of الإكتئاب and anxiety.
What is Citalopram Used For?
Citalopram is FDA-approved to treat:
- Major depressive disorder (الإكتئاب).
- Anxiety disorders.
It’s also prescribed off-label for:
- Obsessive-compulsive disorder (OCD).
- Panic disorder.
- Post-stroke الإكتئاب.
- إكتئاب in patients with chronic illnesses (e.g., heart disease, kidney failure, or HIV).
Who Should Avoid Citalopram?
Citalopram isn’t for everyone. Talk to your doctor if you:
- Are allergic to citalopram or other SSRIs.
- Take MAOIs (another type of antidepressant) or have recently stopped them (wait 2 weeks).
- Have a history of مشاكل في القلب, especially abnormal heart rhythms (e.g., QT prolongation).
- Are pregnant or breastfeeding (discuss risks vs. benefits with your doctor).
ما هي الآثار الجانبية؟
Common side effects (usually mild and temporary):
- Nausea, upset stomach.
- جفاف الفم.
- Drowsiness or insomnia.
- Sweating.
- Headache.
الآثار الجانبية النادرة ولكن الخطيرة:
- QT prolongation (a heart rhythm issue, especially at doses above 40 mg/day).
- Serotonin syndrome (agitation, rapid heartbeat, high fever—seek help immediately).
- Hyponatremia (low sodium levels, more common in older adults).
- Bleeding or bruising (if taking blood thinners or NSAIDs).
Precautions to Keep in Mind
- ابدأ منخفضًا، وأكمل ببطء: Your doctor may start you at 10–20 mg daily and increase gradually.
- Watch your heart: Avoid doses above 40 mg/day unless closely monitored by your doctor.
- Monitor your mood: Especially in the first weeks, report any worsening الإكتئاب أو أفكار انتحارية.
- Avoid alcohol: It can worsen drowsiness or dizziness.
- Liver/kidney issues? You may need a lower dose.
التفاعلات الدوائية التي يجب تجنبها
Citalopram can interact with other medications. Always tell your doctor if you’re taking:
- MAOIs: يمكن أن يسبب متلازمة السيروتونين.
- مميعات الدم (مثل الوارفارين): Increased bleeding risk.
- مضادات الالتهاب (على سبيل المثال، الإيبوبروفين): May reduce citalopram’s effectiveness and increase bleeding risk.
- CYP2C19 inhibitors (e.g., cimetidine): Can increase citalopram levels and risk of side effects.
- Thioridazine or pimozide: Can cause dangerous heart rhythms.
How to Take Citalopram
- Dosage:
- إكتئاب and anxiety: Start with 10–20 mg daily, increasing to a maximum of 40 mg/day.
- OCD: Higher doses (up to 80 mg/day) may be used under close supervision.
- أشكال: Tablets (scored for easy splitting) and liquid solution.
- Tips: Take once daily, with or without food. Avoid crushing or chewing tablets.
Who Makes Citalopram?
The brand-name version Celexa is manufactured by Lundbeck. Generic versions are also widely available and equally effective.
الأفكار النهائية
Citalopram can be a helpful tool for managing الإكتئاب and anxiety, but it’s not a one-size-fits-all solution. Work closely with your doctor to find the right dose and monitor for side effects. And remember—it may take 4–6 weeks to feel the full benefits. Stay patient, stay informed, and prioritize your mental health!
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