Everything You Need to Know About Fluvoxamine (Luvox)
If you or someone you know is struggling with OCD or anxiety, you might have heard of fluvoxamine. Known by the brand name Luvox, this medication is part of the SSRI family, commonly used to balance brain chemistry. Let’s simplify what you need to know about how it works, who it’s for, and how to use it safely.
What is Fluvoxamine?
Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI). It helps boost serotonin—a “feel-good” brain chemical—by preventing your brain from reabsorbing it too quickly. Think of it like keeping more serotonin available to improve mood, reduce anxiety, and calm obsessive thoughts. Unlike some SSRIs, fluvoxamine also interacts with “sigma 1 receptors” in the brain, which may explain its added benefits for anxiety and certain types of اكتئاب.
What is Fluvoxamine Used For?
FDA-approved uses include:
- Obsessive-compulsive disorder (OCD) (for adults and children).
- Social anxiety disorder (using the controlled-release form, Luvox CR).
It’s also prescribed off-label for:
- اكتئاب (widely used outside the U.S.).
- Panic disorder, اضطراب ما بعد الصدمة, and generalized anxiety.
- Managing anxiety in children and teens.
- Hot flashes in perimenopausal women.
Who Should Avoid Fluvoxamine?
Fluvoxamine isn’t for everyone. Talk to your doctor first if you:

- Are allergic to fluvoxamine or SSRIs.
- Take MAOIs (another type of antidepressant) or have recently stopped them (wait 2 weeks).
- Have a history of seizures, bipolar disorder, or liver/kidney disease.
- Are pregnant or breastfeeding (while generally considered safe, discuss risks vs. benefits).
What Are the Side Effects?
Common side effects (usually mild and temporary):
- Nausea, upset stomach.
- Drowsiness or insomnia.
- Dry mouth, sweating.
- Headache.
Rare but serious side effects:
- Serotonin syndrome (agitation, rapid heartbeat, high fever—seek help immediately).
- Seizures.
- Unusual bleeding or bruising (if taking blood thinners).
- Sun sensitivity (wear sunscreen!).
Precautions to Keep in Mind
- Start low, go slow: Your doctor may begin with 50 mg daily and increase gradually.
- Watch your mood: Especially in the first weeks, report sudden mood swings or suicidal thoughts.
- Avoid alcohol: It can worsen drowsiness or dizziness.
- Liver/kidney issues? You may need a lower dose.
- Elderly patients: Often start with smaller doses to avoid side effects.
Drug Interactions to Avoid
Fluvoxamine can interact with many medications. Always tell your doctor if you’re taking:
- Blood thinners (e.g., warfarin): Increased bleeding risk.
- Tramadol: Higher chance of seizures.
- Clomipramine (another OCD med): Fluvoxamine can raise its levels, requiring close monitoring.
- Caffeine or theophylline (asthma drugs): Fluvoxamine may increase their effects.
How to Take Fluvoxamine
- Dosage:
- OCD: Start with 50 mg daily, increasing weekly to 100–300 mg.
- Social anxiety (Luvox CR): 100 mg once daily at bedtime.
- أشكال: Immediate-release (taken 1–2 times daily) or controlled-release (CR, taken once daily).
- Tips: Take with food to reduce stomach upset. Don’t crush or chew CR capsules.
Who Makes Fluvoxamine?
The brand-name version Luvox is manufactured by Jazz Pharmaceuticals. Generic versions are also widely available and equally effective.
Final Thoughts
Fluvoxamine can be a game-changer for OCD and anxiety, but it’s not one-size-fits-all. Work closely with your doctor to find the right dose and monitor for side effects. And remember—it may take 4–6 weeks to feel the full benefits. Stay patient, stay informed, and prioritize your mental health!
Disclaimer: This article is for informational purposes only. Always consult your healthcare provider before starting, stopping, or changing medications.